COURSE:

NURS-6630N: Approaches to Treatment


This week, you will create a Medication Study Guide to share with your peers. This guide is intended to be a useful learning tool for you to use as you prepare for your clinical courses.

You will be assigned one of the following medications to create your guide:

Chlorpromazine Fluphenazine Haloperidol Loxapine Perphenazine
Aripiprazole Asenapine Clozapine Iloperidone Olanzapine
Paliperidone Quetiapine Risperidone Ziprasidone Lurasidone
Brexpiprazole Cariprazine Lumateperone Benztropine Propranolol
Deutetrabenazine Valbenazine      

The Assignment

Create a 3- to 4-page (excluding visual elements) Medication Study Guide for your assigned psychotropic medication agents that may be utilized by you and colleagues for study. Your medication guide should be in the form of an outline and should include a title page, citations, and references. You should incorporate visual elements, such as concept maps, charts, diagrams, images, color coding, mnemonics, and/or flashcards. Be creative!

Note: Your Medication Study Guide should not be in the format of an APA paper.

Also Note: Your guide should be informed by the FDA-Approved and Evidenced-Based, Clinical Practice Guidelines Research.

Areas of importance that you should address—but are not limited to—include:

 

Solution

Patient Medication Guide: Deutetrabenazine

Description of  Deutetrabenazine

 

Brand name : Austedo, Austedo XR

Generic name: Deutetrabenazine

FDA indication:  

v It is used to treat chorea that is associated with Huntington’s disease.

v Also approved for tardive dyskinesia in adult patients (U.S. Food and Drug Administration, n.d

Non-FDA uses v Studies have also reported that  it can be used to treat   tics associated with Tourette syndrome (Coffey et al., 2021)
Drug classification This drug is a vesicular monoamine transporter2 (VMAT2) inhibitor.
Mechanism of action

Works by reducing the action of the action of VMAT2 thereby reducing the levels of monoamines in the synaptic cleft.   Ideally, VMAT2 is involved in the packaging of monoamines such as norepinephrine, serotonin, and dopamine into vesicles.  Deutetrabenazine metabolites namely the αdihydrotetrabenazine [HTBZ] and β-HTBZ) are considered as reversible inhibitors of VMAT2. Therefore, they lead to a decrease in the uptake of monoamines into the synaptic vessels as well as depletion of the monoamine stores (FDA, n.d.)

 

 

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