COURSE:

NURS-6630N: Approaches to Treatment


Construct a 5- to 6-page paper discussing each of the four traditional mood stabilizer medications: carbamazepine, lamotrigine, lithium, and valproate products. Support your answers with five (5) evidence-based, peer-reviewed scholarly literature.

Note: APA style format will apply.

Your paper should include the following for each:

 

Solution

Mood Stabilizers

Mood stabilizers are commonly used in the management of bipolar disorder. Precisely, they help in managing mood swings such as mania, hypomania as well as depression. However, it is important to take into account several factors when prescribing mood stabilizers. In light of this, this paper discusses the consideration for prescribing mood stabilizers.

Mechanism of Action

Carbamazepine is believed to work through two mechanisms namely: enhancing sodium channel inaction through the reduction of high-frequency repetitive firing of action potential as well as action on synaptic transmission (Lattanzi & Belcastro, 2020).  Lamotrigine works by partially blocking the calcium channels and sodium channels which in turn decreases the release of glutamate (Costa & Vale, 2023). A number of studies have proposed that lithium inhibits glycogen synthase kinase-3 β, blocks the binding of serotonin to its receptors as well as alters the release and uptake of glutamate.  Valproic acid exerts its therapeutic effect by………………………..$10

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