Question 1
Which dopamine pathway is associated with positive symptoms of schizophrenia?
nigrostriatal pathway
mesolimbic pathway
tuberoinfundibular pathway
mesocortical pathway
Question 2
A major current hypothesis for the cause of schizophrenia proposes that N-methyl-daspartate
(NMDA) receptors may be which of the following?
hypofunctional
hyperfunctional
Major current hypothesis for the cause of schizophrenia proposes that glutamate activity
at N-methyl-d-aspartate (NMDA) receptors is hypofunctional due to abnormalities in the
formation of glutamatergic NMDA synapses during neurodevelopment.
Question 3
A 34-year old male recently began experiencing breast secretions while receiving
risperidone . Which dopamine pathway is associated with this side effect?
mesolimbic pathway
mesocortical pathway
tuberoinfundibular pathway
nigrostriatal pathway

Question 4
A 44-year-old woman is initiated on an atypical antipsychotic for the treatment of
schizophrenia. Regarding affinity, atypical antipsychotics demonstrate which of the
following most often?
Correct Answer
Atypical antipsychotics have higher affinity for serotonin 2A receptors than for dopamine
2 receptors.
You Answered
Atypical antipsychotics have higher affinity for dopamine 2 receptors than for serotonin
2A receptors.
Atypical antipsychotics have equal positive symptom antipsychotic actions and low
extrapyramidal symptoms.

Question 5
Select the only antipsychotic which reduces the risk of suicide in clients with
schizophrenia.
lurasidone
lithium

clozapine
olanzapine………………………………………….ALL CORRECT ANSWERS FOR $5