General Instructions
Download the neurotransmitter table and complete the required information using the template.
Include the following sections (detailed criteria listed below and in the grading rubric)
- For each neurotransmitter and receptor type, complete the following columns:
- Location/function/effects/symptoms of excess or deficit
- Distribution
- Drug classes that target this neurotransmitter or receptor
- All neurotransmitters and receptor types: Specific medications that target this neurotransmitter or receptor
Solution
| Neuro transmitter | Receptor Subtype | Location/Function/Effects
/symptoms of excess or deficit if applicable |
Distribution (ie: CNS/PNS,
GI, vascular) |
Drug classes that target this neurotransmitter or
receptor |
Specific medications that target this neurotransmitter or receptor |
| Glutamate | AMPA | Ligand-gated ion channels Regulates cell excitability by allowing the flow of calcium and sodium ions into the cell. Located at the CNS in neurons and glia. Excess has resulted in schizophrenia, epilepsy,
and mania. |
CNS | NMDA
glutamate antagonist Barbiturates Antiepileptics |
Memantine Dextromethorphan Dextromethadone Parampanel Ketamine |
| NMDA | Ligand-gated ion channels, reinforces synapses and involved in compelling memory formation. Excess is correlated with memory and learning impairments, psychosis, and excitotoxic brain injury. | CNS | NMDA receptor antagonist Antipsychotics Loop Diuretics Opiates Antidepressants | Methadone Dextropropoxyphene Ketobemidone Furosemide
Haldol Tramadol Memantine Amantadine Ketamine Dextromethorphan |
……………………………..$10